#3478 THE EFFECT ON NET ULTRAFILTRATION WHEN TRANSFERRING PATIENTS FROM NOCTURNAL INTERMITTENT (NIPD) TO CONTINUOUS CYCLING PERITONEAL DIALYSIS (CCPD)

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چکیده

Abstract Background and Aims Peritoneal Dialysis (P.D.) Adequacy includes a variety of targets such as the sufficient uremic toxins removal (Κt/V), patients’ euvolemia, acid-base electrolyte balance etc.. Based on incremental PD prescription NIPD is often reasonable modality choice when there adequate Residual Renal Function (RRF). Eventually due to RRF decrease patients need increase their adequacy by adding solution during day i.e Icodextrin (CCPD). The aim this study was evaluate alteration Cyclers’ ultrafiltration(UF) well Total Ultrafiltration (sum Cycler ultrafiltration UF initial drainage) transferring from CCPD Method This single center retroprospective 16 (m = 9,f 7). These were transferred inadequate adequacy. mean age 53.4±19 years, duration 74.3±25.7 months Solute Transfer Rate (PSTR-D/Pcr) 0.69±0.12. We evaluated small solute clearance (Kt/V – t:total,p:peritoneal,r:renal), (eGFR, Vurine), Cycler’ ultrafiltration, drainage sum them (Total UF) three consecutive days before initiation after initiation. cycler treatment program remain constant all received an volume 1000 ml with Icodextrin. Results compared alterations Paired t-Test (normal distripution) found statistically significant improvement peritoneal fraction Kt/V applying (p 0.01), other hand we Cycler's (p<0.05) without any in urine's volume. Additionally, regression analysis correlation between PSTR ΔUF(UFNIPD-UFCCPDtotal) showing that faster transporter greater loss 0.035, R 0.58). Conclusion Transferring problems improves clearances but some cases risk for total important may lead overhydration. It necessary contact perspective studies hydration status evaluation ie Bioimpedance Spectroscopy.

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2023

ISSN: ['1460-2385', '0931-0509']

DOI: https://doi.org/10.1093/ndt/gfad063c_3478